Investigation of the early intestinal microflora in premature infants with/without necrotizing enterocolitis using two different methods
نویسندگان
چکیده
منابع مشابه
Role of Intestinal Microflora on Necrotizing Enterocolitis in Preterm Infants
Despite overall decreasedmortality andmorbidity in preterm very low-birth-weight (VLBW:<1,500 g) infants over the past decades, necrotizing enterocolitis (NEC), a devastating emergency intestinal disease in preterm VLBW infants, remains 5 to 6% and even increase despite much effort on peri-postnatal care.1 More worrisome, approximately 20 to 30% of VLBW infants with NECwill die2 and the remaini...
متن کاملEffects of Probiotic Lactobacillus Reuteri (DSM 17938) on the Incidence of Necrotizing Enterocolitis in Very Low Birth Weight Premature Infants
Background: Feeding intolerance is a common problem among premature infants. There is limited information on the safety and effects of oral probiotic supplements, especially products containing Lactobacillus reuteri, and the incidence of necrotizing enterocolitis (NEC) in low birth weight preterm infants. This study aimed to evaluate the effects of Lactobacillus reuteri on the gastrointestinal ...
متن کاملPlasma D-lactate Levels in Necrotizing Enterocolitis in Premature Infants
BACKGROUND D-Lactate is normally present in the blood of humans at nanomolar concentrations due to methylglyoxal metabolism; millimolar D-lactate concentrations can arise due to excess gastrointestinal microbial production. OBJECTIVES To examine the levels of plasma D-lactate in the necrotizing enterocolitis in premature infants. PATIENTS AND METHODS 128 premature infants were divided into ...
متن کاملSIGIRR genetic variants in premature infants with necrotizing enterocolitis.
Necrotizing enterocolitis (NEC) is a severe form of bowel disease that develops in premature infants. Although animal data and human studies suggest that aberrant activation of the intestinal immune system contributes to NEC, the pathogenesis remains unclear. We hypothesized that inherited defects in the regulation of Toll-like receptor signaling can contribute to NEC susceptibility in prematur...
متن کاملDysbiosis Anticipating Necrotizing Enterocolitis in Very Premature Infants
BACKGROUND Necrotizing enterocolitis (NEC) is a devastating inflammatory bowel disease of premature infants speculatively associated with infection. Suspected NEC can be indistinguishable from sepsis, and in established cases an infant may die within hours of diagnosis. Present treatment is supportive. A means of presymptomatic diagnosis is urgently needed. We aimed to identify microbial signat...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 2011
ISSN: 0031-3998,1530-0447
DOI: 10.1038/pr.2011.1